HVEM Antibody

Catalog # CA006

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Description

The mammalian tumor necrosis factor receptor (TNFR) family consists of 10 cell-surface proteins that regulate development and homeostasis of the immune system. HVEM (also known as TNFRSF14, TR2, ATAR, HVEA, HVEM, or LIGHTR) was also identified as a mediator of herpesvirus entry into mammalian cells. The cytoplasmic region of HVEM bound to several members of the TNFR-associated factor (TRAF) family, namely TRAF1, TRAF2, TRAF3, and TRAF5. Transient transfection into human 293 cells caused marked activation of nuclear factor- B (NF- B), a transcriptional regulator of multiple immunomodulatory and inflammatory genes.

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Images


Western blot analysis of extracts of Raji cell line, using HVEM antibody, catalog # CA006.

 

Product Details

Catalog #: CA006
Clone ID: Polyclonal
Host species: Rabbit
Ig subclass: IgG
Immunogen: Recombinant protein of human HVEM
UniProt ID: Q92956
Gene ID: 8764
Synonyms: TNFRSF14; ATAR; HVEA; HVEM; LIGHTR; TR2;
Calculated MW: 30 kDa
Observed MW: Refer to figure
Species Reactivity: Human
Applications: WB, IHC
Recommended dilutions: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
Purification Method: Affinity purified
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

100 ul - $255

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