EGFR Antibody (RM294)

Catalog #CA017



EGFR is a cell-surface receptor tyrosine kinase, and activated by binding of its specific ligand, such as epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha), EGFR overexpression or overactivity have associated with a number of cancers, including the lung cancer and colon cancer. The identification of EGFR as a driver gene has led to the development of anticancer therapeutics agents, including Gefitinib, Erlotinib, Afatinib, Osimertinib (AZD9291) and Cetuximab.



IHC staining of formalin fixed and paraffin embedded human breast cancer tissue sections using EGFR antibody (clone RM294) at a 1:200 dilution.

Western Blot of HeLa cell lysates using EGFR antibody (clone RM294) at a 1:200 dilution.

Product Details

Catalog #: CA017
Clone ID: RM294
Clonality: Monoclonal
Host species: Rabbit
Ig subclass: IgG
Immunogen: A peptide corresponding to the C-terminus of human EGF Receptor (c-ErbB-1)
UniProt ID: P00533
Gene ID: 1956
Synonyms: Epidermal growth factor receptor, ERBB, ERBB1, HER1
Observed MW: Refer to figure
Species Reactivity: Human
Specificity: This antibody reacts to human EGF Receptor (c-ErbB-1). No cross reactivity with HER2, HER3, or HER4.
Applications: IHC, WB
Recommended dilutions: IHC: 1:100 -1:200
WB: 1:200 - 1:500
Purification Method: Protein A affinity purified from an animal origin–free culture supernatant
Buffer: 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Storage Conditions: Stable for 1 year at -20.0°C from date of receipt.

100 ul - $325

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