CTLA-4 Antibody

Catalog # CA005

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Description

CTLA-4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [RefSeq, Jul 2008]

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Images


Western blot analysis of extracts of various cell lines, using CTLA4 antibody, catalog # CA005.

 

Product Details

Catalog #: CA005
Clone ID: Polyclonal
Host species: Rabbit
Ig subclass: IgG
Immunogen: A synthetic peptide of human CTLA-4
UniProt ID: P16410
Gene ID: 1493
Synonyms: CTLA4; CD; CD152; CELIAC3; GRD4; GSE; ICOS; IDDM12
Calculated MW: 25 kDa
Observed MW: Refer to figure
Species Reactivity: Human, Mouse
Applications: WB
Recommended dilutions: WB: 1:500 - 1:2000
Purification Method: Affinity purified
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

100 ul - $255

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