CD27 Antibody

Catalog # CA003

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Description

CD27 is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq]

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Images


Western blot analysis of extracts of various cell lines, using CD27 antibody, catalog # CA003.


Immunofluorescence analysis of MCF7 cell using CD27 antibody, catalog # CA003 (blue: DAPI for nuclear staining).

Product Details

Catalog #: CA003
Clone ID: Polyclonal
Host species: Rabbit
Ig subclass: IgG
Immunogen: Recombinant protein of human CD27
UniProt ID: P26842
Gene ID: 939
Synonyms: MGC20393; S152; T14; TNFRSF7; Tp55;
Calculated MW: 50 kDa
Observed MW: Refer to figure
Species Reactivity: Human, Mouse, Rat
Applications: WB, IHC, IF
Recommended dilutions: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
Purification Method: Affinity purified
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

100 ul - $255

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