AACR New Horizons 2017 Scientific Poster Session

November 7, 2017

A27

Tumor-infiltrating MDSCs seem predictive of antitumor activity of a PD-1 antibody in a population-based syngeneic mouse tumor trial

Session: Poster Session A
Session Time: 13:00-15:30pm
Session Location: Ballroom 1-3

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A63

Establishment of Kras (G12D)/Trp53 null/Pdx1-cre (KPC) mouse allograft tumor models to facilitate preclinical efficacy evaluation of combinatory immunotherapies

Session: Poster Session A
Session Time: 13:00-15:30pm
Session Location: Ballroom 1-3

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A64

MuScreen™ allows profiling of antitumor efficacy and biomarker readouts of drug candidates using well-characterized syngeneic models

Session: Poster Session A
Session Time: 13:00-15:30pm
Session Location: Ballroom 1-3

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A65

Commensal microbiota is involved in anti-PD-1 mAb-mediated antitumor activity in a preclinical tumor model

Session: Poster Session A
Session Time: 13:00-15:30pm
Session Location: Ballroom 1-3

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November 8, 2017

B20

Survival analysis for PDX mouse clinical trials

Session: Poster Session B
Session Time: 13:00-15:30pm
Session Location: Ballroom 1-3

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B21

Determining combination effects in cell based assays

Session: Poster Session B
Session Time: 13:00-15:30pm
Session Location: Ballroom 1-3

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B59

Establishment of de novo and viral induced B lymphoma PDX models to evaluate efficacy of the BTK inhibitor ibrutinib

Session: Poster Session B
Session Time: 13:00-15:30pm
Session Location: Ballroom 1-3

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B73

Efficacy assessment of investigation human OX40 agonistic antibodies with human OX40 knock-in mouse models

Session: Poster Session B
Session Time: 13:00-15:30pm
Session Location: Ballroom 1-3

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B74

Development, characterization, and optimization of PBMC-humanized mouse tumor models, MiXeno™, as a valid platform to evaluate in vivo activities of immuno-oncology drug candidates

Session: Poster Session B
Session Time: 13:00-15:30pm
Session Location: Ballroom 1-3

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B75

Flow-based phenotyping of tumor-infiltrating immune cells in novel I/O models

Session: Poster Session B
Session Time: 13:00-15:30pm
Session Location: Ballroom 1-3

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B78

CD47 expression predicts efficacy of macrophage-mediated phagocytosis of tumor cells

Session: Poster Session B
Session Time: 13:00-15:30pm
Session Location: Ballroom 1-3

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B80

Pharmacological inhibition of syngeneic murine cancer cell proliferation by checkpoint inhibitors in combination with targeted agents

Session: Poster Session B
Session Time: 13:00-15:30pm
Session Location: Ballroom 1-3

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