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AACR 2020 - CrownBio Posters

1800

Systematic genomic analysis of matched PDX, PDX-derived organoids (PDXO), and PDX-derived cell lines (PDXC)

Session Category: Molecular and Cellular Biology/Genetics
Session Title: Genomic Profiling of Tumors 1

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LB-0070

The emergence of tumor organoid engineering as a powerful tool for drug efficacy and mechanism of action profiling

Session Category: Tumor Biology
Session Title: LB-Tumor Biology 1

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27680

Development of a bioluminescent pancreatic orthotopic KPC model for immuno-oncology drug discovery

Session Category: Tumor Biology
Session Title: Mouse Models of Human Cancer in Imaging and Therapeutics

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27880

Characterization of a panel of orthotopic syngeneic models using bioluminescent imaging for the evaluation of immuno-oncology therapies

Session Category: Tumor Biology
Session Title: New Imaging-Based Approaches to Plan, Monitor, and Augment Cancer Treatment

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27980

Cancer stem cell (CSC) profiling of colorectal cancer (CRC) patient-derived xenograft (PDX) and corresponding in vitro organoid models by multiplex IHC

Session Category: Tumor Biology
Session Title: Patient-Derived Organoids and Xenografts

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32280

An online tool to balance baseline covariates for mouse clinical trials

Session Category: Bioinformatics and Systems Biology
Session Title: Data and Analytical Resources and Standards for Next-Generation Sequencing and Omics

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45750

Proof of concept with universal mRNA vaccines in various mouse tumor models

Session Category: Immunology
Session Title: Vaccines

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56140

Combination anti-TIGIT and anti-PD-1 antibodies enhance antitumor response in PD-1/TIGIT double HuGEMM™ model engrafted with mouse syngeneic tumors

Session Category: Immunology
Session Title: Novel Animal Models

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56150

Anti-human CD47 antibodies inhibit hCD47-MC38 tumor growth in hCD47/hSIRPα double knock-in mice

Session Category: Immunology
Session Title: Novel Animal Models

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56160

Characterization of a spectrum of DTR models for conditional depletion of specific immune cell lineages

Session Category: Immunology
Session Title: Novel Animal Models

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59630

NGS-based murine pan-cancer gene expression panel for immuno-oncology and tumor microenvironment studies

Session Category: Molecular and Cellular Biology/Genetics
Session Title: Immune, Stem Cell, Growth Promoting, and Metastatic Signaling in Cancer

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Collaborative Posters

Presented by: Biognosys & CrownBio

9270

Deep proteomic profiling of CD4+ and CD8+ T cell-depleted tumor models in PD-1 treatment

Session Category: Immunology
Session Title: Immune Checkpoints 1

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Presented by: Eisai, Compass Therapeutics, & CrownBio

55220

Evaluation of eribulin-induced alterations of the intact immune cell landscape in spleens and tumors from tumor-bearing immunocompetent mice

Session Category: Immunology
Session Title: Immune Response to Therapies 1

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