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AACR 2019 - CrownBio Posters

Sunday Mar 31, 2019

1:00 PM - 5:00 PM

0870

Recapitulating the orthotopic tumor microenvironment using bioluminescent syngeneic models in immune competent mice for checkpoint inhibitor interrogation

Poster Section: 4  |  Poster Board Number: 6
Session Category: Tumor Biology
Session Title: Developmental Phenotypes and Molecular Imaging

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Monday Apr 1, 2019

8:00 AM - 12:00 PM

1060

Establishment of a panel of prostate patient-derived xenograft (PDX) models and evaluation of anti-androgen therapy

Poster Section: 4  |  Poster Board Number: 11
Session Category: Tumor Biology
Session Title: Human in Mouse

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1443

Sensitive detection and quantification of CAR-T cells in treated patients

Poster Section: 21  |  Poster Board Number: 24
Session Category: Immunology
Session Title: Adoptive Cell Therapy 1

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1503

Effect of immune cell depletion on response to PD-1 treatment in syngeneic models

Poster Section: 23  |  Poster Board Number: 28
Session Category: Immunology
Session Title: Cellular Interactions in the Tumor Microenvironment

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1:00 PM - 5:00 PM

1925

Establishment and characterization of 3D cancer organoids as clinically relevant ex vivo drug screening tools for cancer translational research and drug discovery

Poster Section: 4  |  Poster Board Number: 9
Session Category: Tumor Biology
Session Title: Models and Drug Discovery

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2342

Experimental modeling of acute- and chronic-GvHD by xenotransplanting human donor PBMCs or cord blood CD34+ cells (HSC) into NSG™ mice

Poster Section: 23  |  Poster Board Number: 11
Session Category: Immunology
Session Title: Cancer and Inflammation

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2375

Developing double knock-in models of human immune checkpoint targets (dKI HuGEMM™) for efficacy assessment of combinatorial therapeutic antibodies

Poster Section: 24  |  Poster Board Number: 29
Session Category: Immunology
Session Title: Molecular Mechanisms in the Immune Response to Cancer

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Tuesday Apr 2, 2019

8:00 AM - 12:00 PM

3418

A NGS-based SNP array for the identification of human xenograft tumors, mouse homograft tumors, human and mouse cell lines, and organoids

Poster Section: 32  |  Poster Board Number: 19
Session Category: Molecular and Cellular Biology / Genetics
Session Title: Cancer Genomics 4

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1:00 PM - 5:00 PM

4124

Expression of co-inhibitory molecules may impact immune checkpoint therapies

Poster Section: 24  |  Poster Board Number: 27
Session Category: Immunology
Session Title: Immune Checkpoints 2

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Wednesday Apr 3, 2019

8:00 AM - 12:00 PM

4609

Establishment of sarcoma PDX models with various subtypes for drug efficacy evaluation

Poster Section: 6  |  Poster Board Number: 4
Session Category: Tumor Biology
Session Title: Mouse Models

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4610

Prognostic impact of KRAS driver mutations and GSTT1 expression in colorectal cancer to FOLFOX treatment

Poster Section: 6  |  Poster Board Number: 5
Session Category: Tumor Biology
Session Title: Mouse Models

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4613

Mathematical modeling of tumor growth in mouse models

Poster Section: 6  |  Poster Board Number: 8
Session Category: Tumor Biology
Session Title: Mouse Models

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4621

Developing genetically modified homograft models of mouse prostate cancer for efficacy evaluation of combinatory immunotherapies

Poster Section: 6  |  Poster Board Number: 16
Session Category: Tumor Biology
Session Title: Mouse Models

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4976

Ex vivo functional characterization and in vivo efficacy validation of human CD40 agonistic antibodies in the human CD40 knock-in model (CD40 HuGEMM™)

Poster Section: 23  |  Poster Board Number: 29
Session Category: Immunology
Session Title: Adaptive Immune Cells in the Tumor Microenvironment

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5111

HuPharm: An interactive data analysis platform for preclinical studies

Poster Section: 30  |  Poster Board Number: 19
Session Category: Bioinformatics and Systems Biology
Session Title: Methods and Tools for Cancer Analysis

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