AACR 2017- CrownBio Posters

Sunday Apr 2, 2017

396

Determining gene copy number variation via whole exome sequencing (WES) datasets from patient-derived xenografts

Session Category: Molecular and Cellular Biology / Genetics
Session Title: Genomic Analyses across Cancer Types
Session Date and Time: Sunday Apr 2, 2017 1:00 PM - 5:00 PM
Location: Convention Center, Halls A-C, Poster Section 16
Poster Board Number: 22

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Monday Apr 3, 2017

1647

Validation and characterization of MiXenoTM humanized mouse models for immuno-oncology

Session Category: Immunology
Session Title: Tumor Microenvironment and Checkpoints
Session Date and Time: Monday Apr 3, 2017 8:00 AM - 12:00 PM
Location: Convention Center, Halls A-C, Poster Section 27
Poster Board Number: 25

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1658

Establishment of a CD137 humanized mouse model for efficacy assessment of agonistic anti-CD137 therapeutic antibodies

Session Category: Immunology
Session Title: Tumor Models and Assays
Session Date and Time: Monday Apr 3, 2017 8:00 AM - 12:00 PM
Location: Convention Center, Halls A-C, Poster Section 28
Poster Board Number: 6

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1665

MuScreenTM: An efficient and cost-effective in vivo screening platform using a panel of well-charcterized syngeneic tumor models

Session Category: Immunology
Session Title: Tumor Models and Assays
Session Date and Time: Monday Apr 3, 2017 8:00 AM - 12:00 PM
Location: Convention Center, Halls A-C, Poster Section 28
Poster Board Number: 13

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1829

Evaluation of checkpoint inhibitors on tumor infiltrating immune cells in the orthotopic and metastatic tumor microenvironment using bioluminescent syngeneic cell line models

Session Category: Tumor Biology
Session Title: Cell Culture and Animal Models of Cancer 2
Session Date and Time: Monday Apr 3, 2017 8:00 AM - 12:00 PM
Location: Convention Center, Halls A-C, Poster Section 38
Poster Board Number: 3

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2008

Intestinal microbiota may dynamically influence anti-PD-L1 immunotherapy

Session Category: Tumor Biology
Session Title: Tumor Microenvironment 2
Session Date and Time: Monday Apr 3, 2017 8:00 AM - 12:00 PM
Location: Convention Center, Halls A-C, Poster Section 44
Poster Board Number: 23

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2696

Anti-PD-1 mAb treatment induces significant gut microbiota changes in the CT-26 colon cancer syngeneic model

Session Category: Immunology
Session Title: Inflammation and Cancer
Session Date and Time: Monday Apr 3, 2017 1:00 PM - 5:00 PM
Location: Convention Center, Halls A-C, Poster Section 27
Poster Board Number: 25

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2807

Developing a variety of primary mouse tumor allograft models for the evaluation of PARP inhibitors

Session Category: Tumor Biology
Session Title: Cell Culture and Animal Models of Cancer 3
Session Date and Time: Monday Apr 3, 2017 1:00 PM - 5:00 PM
Location: Convention Center, Halls A-C, Poster Section 38
Poster Board Number: 9

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2811

Comparative study of anti-PD-1 and CSF1R inhibition on tumor infiltrating lymphocytes and macrophage populations across a panel of syngeneic tumor models

Session Category: Tumor Biology
Session Title: Cell Culture and Animal Models of Cancer 3
Session Date and Time: Monday Apr 3, 2017 1:00 PM - 5:00 PM
Location: Convention Center, Halls A-C, Poster Section 38
Poster Board Number: 13

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2824

Validation of a panel of patient-derived xenograft models for prostate cancer and cell line models for preclinical drug evaluation

Session Category: Tumor Biology
Session Title: Cell Culture and Animal Models of Cancer 3
Session Date and Time: Monday Apr 3, 2017 1:00 PM - 5:00 PM
Location: Convention Center, Halls A-C, Poster Section 38
Poster Board Number: 26

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Tuesday Apr 4, 2017

4203

Kinase inhibitor demonstrates efficacy in patient-derived xenograft model of fibrolamellar hepatocellular carcinoma featuring DNAJB1-PRKACA gene fusion

Session Category: Experimental and Molecular Therapeutics
Session Title: Targeting Protein Kinases and DNA Repair
Session Date and Time: Tuesday Apr 4, 2017 1:00 PM - 5:00 PM
Location: Convention Center, Halls A-C, Poster Section 7
Poster Board Number: 26

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4534

Theory and methodology for the design and analysis of PDX mouse clinical trials

Session Category: Bioinformatics and Systems Biology
Session Title: Modeling and Algorithms
Session Date and Time: Tuesday Apr 4, 2017 1:00 PM - 5:00 PM
Location: Convention Center, Halls A-C, Poster Section 24
Poster Board Number: 8

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4707

Evaluation of efficacy and immune response to PD-1 checkpoint inhibition in human immune-reconstituted mice using patient-derived xenograft models

Session Category: Clinical Research
Session Title: Immunomodulatory Agents and Therapeutics
Session Date and Time: Tuesday Apr 4, 2017 1:00 PM - 5:00 PM
Location: Convention Center, Halls A-C, Poster Section 30
Poster Board Number: 23

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Wednesday Apr 5, 2017

5597

Genomic profiling of syngeneic mouse cell lines and model in vitro screen against checkpoint inhibitors and targeted agents for preclinical applications

Session Category: Immunology
Session Title: Enzymes and Hormones and Metabolism in Tumor Immunity
Session Date and Time: Wednesday Apr 5, 2017 8:00 AM - 12:00 PM
Location: Convention Center, Halls A-C, Poster Section 24
Poster Board Number: 29

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