The mission for Quantitative Biology is to provide medium throughput and quantitative evaluation of compounds efficacy in various biological systems. Such data will provide guidance for the reiterative effort in compound optimization.
Our capabilities in Quantitative Biology include:
- Purified enzyme and cell-based assays
- Medium throughput fragment compound screening
- Potency and specificity analysis for compound SAR modification
- In vivo target inhibition (IVTI) analysis
- Mechanism of action analysis
* Mean-Ratio (MR) =1.01, Ratio Limits (RLs) =(0.94-1.08)
* Minimum Significant Ratio (MSR) =1.372, Limits of Agreement (LsA) =(0.73-1.38)
Sample validation data for enzymatic assay