XenoSelect Panel™ in vitro screening
Take the guesswork out of your efficacy study.XenoSelect PanelTM consists of 40 cancer cell lines commonly used for in vitro drug activity screening, which serves as the first step to profile compound activity in vitro. For each cell line in the XenoSelectTM Panel, we have validated animal xenograft models, ValidateXenoTM, for later stage in-vivo pharmacology studies, thus significantly reducing the lead time from cell based assay to in-vivo pharmacology.
| Cancer type | Cell lines |
|---|---|
| Breast cancer | MCF-7, MDA-MB231, SKBR3, BT474, MCF-7-218 (Her2++) |
| Lung cancer | A549, NCI-H460, NCI-H226, SK-MES1, Calu6 |
| Colorectal cancer | HT-29, HCT-116,DLD-1, SW620, LoVo, Colo205, H1975 |
| Prostate cancer | DU-145, PC-3, LNCaP |
| Pancreatic cancer | MIAPACA-2, Bx-PC-3, PANC-1 |
| Liver cancer | HepG2, SK-HEP-1, Hep3B |
| Melanoma | A375, SK-MEL-5 |
| Ovarian cancer | SKOV3, OVCAR3 |
| Glioblastoma | U87MG, LN-229 |
| Leukemia | K562, HL60 |
| Multiple myeloma | RPMI 8226, OPM2 |
| Kidney cancer | 786-O |
| Fibrosarcoma | HT-1080 |
| Osteosarcoma | 143b |
| Gastric cancer | MGC803, BGC823, NCI-N87 |
| H&N cancer | CNE2 |
| Oral cancer | KB |