Cell Based Assays

XenoSelect Panel™ in vitro screening

XenoSelect Panel^TM consists of 40+ cancer cell lines commonly used for in vitro drug activity screening, which serves as the first step to profile compound activity in vitro. For each cell line in the XenoSelect Panel^TM, we have a matched validated tumor models for later stage in-vivo pharmacology studies, thus significantly reducing the lead time from cell based assay to in-vivo pharmacology.

PrimePanel ™ in vitro screening

Prime Panel is designed to understand comprehensive drug response profile within a specific cancer type. Each Prime Panel consists of cancer cell lines from the same tissue histology, including both ATCC/DSMZ cell lines and primary cancer cell lines derived from our in-house HuPrime^TM platform.

Omni Panel™ in vitro screening

We have collected over 300 cancer cell lines, as well as our proprietary primary cancer cells which are backed by detailed patient clinical information and extensive cDNA microarray data. The Omni Panel will provide the most comprehensive analysis of lead compound in vitro, and important resource for predictive biomarker discovery.

Cancer Stem Cell - a new resource for tumor initiating cell based assays

Cancer Stem Cells (CSC), also thought of as tumor initiating cells, have altered the landscape of cancer research. Understanding the molecular biology of cancer cells is now essential for developing more effective cancer treatments. CrownBio’s HuPrime™ platform is the eminent resource as the world’s largest collection of human primary tumor tissues for cutting edge discovery and the effect of anti-cancer therapeutics on tumor regrowth.