DMPK

Simple but not basic - only pay for the tests you really need!

Appropriate application of in vivo pharmacodynamic study and drug analysis can dramatically speed drug discovery and development. CrownBio offers in vivo and in vitro pharmacokinetic studies of drugs and drug metabolites with fast turnaround times, which will help you make your decisions faster and reducing your total study costs. Crown Bioscience offers a range of in vivo PK studies, including:


In Vivo DMPK Services

  • Study design covering your PK to Efficacy to PD
  • Studies performed in normal and diseased states in rats , mice, rabbit, guinea pig, dog and non human primates
  • All routes of administration (IP, IV, PO, SC intratracheal, etc.)
  • Continue IV infusion PK for conscious and anesthetized mice, rat and rabbit
  • In vivo Crossover studies for Bioavailability
  • Single, multiple, and cassette dosing
  • Blood and tissue sampling services include collection of serum or plasma, or cerebrospinal fluid and organ removal at necropsy
  • Streamline and immediate queue for efficacy study


Non-GLP Toxicity