Animal Pharmacology

Operating within our Expertise: Oncology.

Crown Bioscience has established multiple in vivo assay systems to evaluate novel anti-cancer compounds. Each assay is designed to understand specific aspects of drug property and its mechanism of action. By accessing our comprehensive capability, our customers can advance development programs in a timely and cost-effective manner. Our highly experienced preclinical team is; focused solely on oncology, works with you to choose the most appropriate study design and screening method for an investigational agent.

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Oncology Experts

ValidatedXeno^TM
- Subcutaneous Tumor Xenografts View images 1, 2
- Orthotopic Tumor models View images 1, 2, 3, 4
- Syngeneic Tumor models
HuPrime^TM Collection
- Human Primary Tumor Xenografts View images 1, 2, 3
Premium Efficacy Models
- Metastatic Tumor Models View images 1, 2, 3
- Angiogenesis Models View images 1, 2, 3, 4
  - Window Chamber
  - Matrigel Plug Assay
- Combination Chemotherapeutic Models

AdvantageServices^TM

Maximum Tolerated Dose Determinations
In Vitro IC50 Determination
Biomarker Services View image

DMPK